固定科研人员/Faculty

张帆/Fan Zhang

发布时间:2015/7/22 浏览量:643

张帆  医学博士  副教授

新疆医科大学基础医学硕士(2002); 首都医科大学影像医学及核医学博士(2007), 导师为首都医科大学宣武医院李坤诚教授; 2007-2010, 南京军区南京总医院医学影像科卢光明教授课题组博士后; 2010-2013,美国国立卫生院(NIH)生物医学与生物影像工程研究所(NIBIB)陈小元(Shawn Chen)教授课题组博士后。作为项目负责人承担2008中国博士后基金和江苏省博士后基金各一项, 2013国家自然科学青年基金一项。作为主要实验者参与国家自然科学基金重点项目和国家自然科学基金国际重大合作项目的研究。在肿瘤和神经系统疾病的分子成像特别是磁共振成像领域积累了较丰富的理论基础和实践经验,并较好的掌握了相关领域的科学前沿和发展方向。

Dr. Zhang received her M.D degree 2007 from the capital university of medical science. From 2010 to 2013, Dr. Zhang joined the Laboratory for Molecular Imaging and Nanomedicine (LOMIN) at the National Institute of Biomedical Imaging and Bioengineering (NIBIB) as a postdoctoral visiting fellow under the supervision of Dr. Shawn Chen. Dr. Zhang’s research is mainly focused on multimodality molecular imaging of tumor and Neurological disorders.

Publications:

2013

  1. Huang X, Zhang F, Zhu L, Choi KY, Guo N, Guo J, Tackett K, Anilkumar P, Liu G, Quan Q, Choi HS, Niu G, Sun YP, Lee S, Chen X. Effect of injection routes on the biodistribution, clearance, and tumor uptake of carbon dots. ACS Nano. 2013 Jul 23;7(7):5684-93.

  1. Cai Y, Zhu L, Zhang F, Niu G, Lee S, Kimura S, Chen X. Non-Invasive Monitoring of Pulmonary Fibrosis by Targeting Matrix Metalloproteinases (MMPs).Mol Pharm. 2013 Apr 22. [Epub ahead of print]

  1. Huang X, Zhang F, Wang H, Niu G, Choi KY, Swierczewska M, Zhang G, Gao H, Wang Z, Zhu L, Choi HS, Lee S, Chen X. Biomaterials. Mesenchymal stem cell-based cell engineering with multifunctional mesoporous silica nanoparticles for tumor delivery.2013 Feb; 34 (7):1772-80.

2012

  1. Fan Zhang, Xinglu Huang, Chunqi Qian, Lei Zhu, Naoki Hida, Gang Niu, Xiaoyuan Chen. SynergisticEnhancement of IronOxideNanoparticle and Gadolinium for Dual-Contrast MRI. Biochemical and Biophysical Research Communications. 2012 Sep;425(4): 886–891

  1. Fan Zhang, Lei Zhu, Xinglu Huang, Guangmin Lu, Gang Niu, Xiaoyuan Chen. Differentiation of Reactive and Tumor Metastatic Lymph Nodes with Diffusion-weighted and SPIO Enhanced MRI. Mol Imaging Biol. 2012 May 16. [Epub ahead of print]

  1. Fan Zhang, Xinglu Huang, Lei Zhu, Ning Guo, Gang Niu, Magdalena Swierczewska, Seulki Lee, Hong Xu, Y. Andrew Wang, Khalid A. Mohamedali, Michael G. Rosenblum, Guangming Lu, Xiaoyuan Chen. Noninvasive Monitoring of Orthotopic Glioblastoma Therapy Response using RGD-Conjugated Iron Oxide Nanoparticles. Biomaterials. 2012 Jul;33(21):5414-22

  1. Xinglu Huang, Fan Zhang (co-first author), Lee, Seulki, Gang Niu, Xiaoyuan Chen. Long-term Multimodal Imaging of Tumor Draining Sentinel Lymph Nodes using Mesoporous Silica-based Nanoprobes. Biomaterials. 2012 Jun;33(17):4370-8.

2011

  1. Fan Zhang, Gang Niu, Xin lin, Orit Jacobson, Ying Ma, Yulong He, Guangming Lu, Xiaoyuan Chen. Imaging tumor-induced sentinel lymph node lymphangiogenesis with LyP-1 peptide. Amino Acids. 2011 Jul 19. [Epub ahead of print]

  1. Fan Zhang, Lei Zhu, Gang Liu, Guangming Lu, Gang Niu, Xiaoyuan Chen. Multimodality imaging to assess tumor apoptosis to Chemotherapy. Theranostics 2011; 1:302-309

  1. Zhu L, Zhang F, Ma Y, Liu G, Kim K, Fang X, Lee S, Chen X. Membrane type matrix metalloproteinases imaging Using a Novel Fluorescent Photoprobe. Molecular Pharmaceutics, DOI: 10.1021/mp2002297

  1. Fan Zhang, Jin Xie, Gang Liu, Yu-long He, Guang-ming Lu, Xiao-yuan Chen. In vivo MRI tracking of cell invasion and migration in a rat glioma model. Mol Imaging Biol. 2011 Aug;13(4):695-701.

  1. Fan Zhang, Guang-ming Lu,Chi-Shing Zee. Comparative study of the sensitivity of ADC value and T(2) relaxation time for early detection of Wallerian degeneration. Eur J Radiol. 2011 Jul;79(1):118-23

  1. Fan Zhang, Gang Niu, Guang-ming Lu , Xiao-yuan Chen. Preclinical Lymphatic Imaging. Mol Imaging Biol. 2011 Aug;13(4):599-612

  1. Xie J, Zhang F, Aronova M, Zhu L, Lin X, Quan Q, Liu G, Zhang G, Choi KY, Kim K, Sun X, Lee S, Sun S, Leapman R, Chen X. Manipulating the power of an additional phase: a flower-like Au-Fe3O4 optical nanosensor for imaging protease expressions in vivo. ACS Nano. 2011 Apr 26;5(4):304351

  1. Xing R, Zhang F, Xie J, Aronova M, Zhang G, Guo N, Huang X, Sun X, Liu G, Bryant LH, Bhirde A, Liang A, Hou Y, Leapman RD, Sun S, Chen X. Polyaspartic acid coated manganese oxide nanoparticles for efficient liver MRI. Nanoscale. 2011 Dec;3(12):4943-5.

  1. Liu G, Xie J, Zhang F, Wang Z, Luo K, Zhu L, Quan Q, Niu G, Lee S, Ai H, Chen X. N-Alkyl-PEI-functionalized iron oxide nanoclusters for efficient siRNA delivery. Small. 2011 Oct 4;7(19):27429

  1. Zhu L, Xie J, Swierczewska M, Zhang F, Lin X, Fang X, Niu G, Lee S, Chen X. Dual-functional, receptor-targeted fluorogenic probe for in vivo imaging of extracellular protease expressions. Bioconjug Chem. 2011 Jun 15;22(6):1001-5. Epub 2011 May 24.

  1. Zhu L, Xie J, Swierczewska M, Zhang F, Quan Q, Ma Y, Fang X, Kim K, Lee S, Chen X. Real-time video imaging of protease expression in vivo. Theranostics. 2011;1:18-27.

  1. Lin, Xin; Xie, Jin; Niu, Gang; Zhang, Fan; Gao, Haokao; Yang, Min; Quan, Qimeng; Aronova, Maria; Zhang, Guofeng; Lee, Seulki; Leapman, Richard; Chen, Xiaoyuan. Chimeric ferritin nanocages for multiple function loading and multimodal imaging. Nano Letters. 2011 Feb 9;11(2):814-9.

  1. Quan Q, Xie J, Gao H, Yang M, Zhang F, Liu G, Lin X, Wang A, Eden HS, Lee S, Zhang G, Chen X. HSA coated iron oxide nanoparticles as drug delivery vehicles for cancer therapy. Mol Pharm. 2011 Oct 3;8(5):1669-76. Epub 2011 Aug 22. 

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