技术人员/Technicians

黄守杰/Shoujie Huang

发布时间:2015/7/22 浏览量:951

黄守杰(Shoujie Huang)  硕士 高级实验师

学习经历

2008年 获厦门大学生物化学与分子生物学硕士学位

1999年 获北京大学公共卫生学院医学学士学位

 

工作经历

2012年 厦门大学公共卫生学院 高级实验师

2011年 厦门大学公共卫生学院 实验师

2004年 厦门大学医学院 实验师

1999年 厦门大学医学院 助理实验师

Tel: 0592-2188393(O);E-mail: huangshoujie@xmu.edu.cn

个人简介

中国民主同盟会会员,中华医学会会员。2006年至今主要从事疫苗临床试验和现场流行病学研究,在疫苗临床试验具有丰富的经验。作为主要研究成员完成国家一类新药戊型肝炎疫苗Ⅲ期临床试验,该疫苗现已获得新药证书和生产文号,成为世界上第一个成功上市的戊肝疫苗。作为主要研究人员主持或参与国家自然科学基金、国家传染病重大科技专项、国家863项目等多个项目。已发表论文20篇,其中SCI论文13篇。

代表性论文

1)  Shu Chen, Zi Zhou, Fei-Xue Wei, Shou-Jie Huang, Zhong Tan, Ya Fang, Feng-Cai Zhu, Ting Wu, Jun Zhang, Ning-Shao Xia. Modeling the long-term antibody response of a hepatitis E vaccine [J]. Vaccine, 2015. (IF:3.624)

2)  Ting Wu, Yue-Mei Hu, Juan Li, Kai Chu, Shou-Jie Huang, Hui Zhao, Zhong-Ze Wang, Chang-Lin Yang, Han-Min Jiang, Yi-Jun Wang, Zhi-Jie Lin, Hui-Rong Pan, Wei Sheng, Fei-Xue Wei, Shao-Wei Li, Ying Wang, Feng-Cai Zhu, Chang-Gui Li, Jun Zhang, Ning-Shao Xia. Immunogenicity and safety of an E. coli–produced bivalent human papillomavirus (type 16 and 18) vaccine: a randomized controlled phase 2 clinical trial [J]. Vaccine, 2015, 33: 3940-3946. (IF:3.624)

3)  Jun Zhang, Xue-Feng Zhang, Shou-Jie Huang, Ting Wu, Yue-Mei Hu, Zhong-Ze Wang, Hua Wang, Han-Min Jiang, Yi-Jun Wang, Qiang Yan, Meng Guo, Xiao-Hui Liu, Jing-Xin Li, Chang-Lin Yang, Quan Tang, Ren-Jie Jiang, Hui-Rong Pan, Yi-Min Li, J. Wai-Kuo Shih, Mun-Hon Ng, Feng-Cai Zhu, Ning-Shao Xia. Long-term efficacy of a hepatitis E vaccine [J]. New England Journal of Medicine, 2015, 372(10): 914-922. (IF: 55.873)

4)  Shou-Jie Huang, Xiao-Hui Liu, Jun Zhang, Mun-Hon Ng. Protective immunity against HEV [J]. Current opinion in virology, 2014, 5: 1-6. (IF: 6.298)

5)  Feng-Cai Zhu, Shou-Jie Huang, Ting Wu, Xue-Feng Zhang, Zhong-Ze Wang, Xing Ai, Qiang Yan, Chang-Lin Yang, Jia-Ping Cai, Han-Min Jiang, Yi-Jun Wang, Mun-Hon Ng, Jun Zhang, Ning-Shao Xia. Epidemiology of Zoonotic Hepatitis E: A Community-Based Surveillance Study in a Rural Population in China [J]. PloS one, 2014, 9(1): e87154. (IF: 3.234, Co-First Author)

6)  Hui Zhao, Zhi-Jie Lin, Shou-Jie Huang, Juan Li, Xiao-Hui Liu, Meng Guo, Jun Zhang, Ning-Shao Xia, Hui-Rong Pan, Ting Wu, Chang-Gui Li. Correlation between ELISA and pseudovirion-based neutralisation assay for detecting antibodies against human papillomavirus acquired by natural infection or by vaccination [J]. Human Vaccines &Immunotherapeutics, 2014, 10(3): 740-746. (IF: 2.366)

7)  Yuemei Hu, Shou-Jie Huang, Kai Chu, Ting Wu, Zhong-Ze Wang, Chang-Lin Yang, Jia-Ping Cai, Han-Min Jiang, Yi-Jun Wang, Meng Guo, Xiao-Hui Liu, Hong-Jiang Huang, Feng-Cai Zhu, Jun Zhang, Ning-Shao Xia. Safety of an Escherichia coli-expressed bivalent human papillomavirus (types 16 and 18) L1 virus-like particle vaccine: An open-label phase I clinical trial [J]. Human vaccines & immunotherapeutics, 2014, 10(2): 469-475. (IF: 2.366, Co-First Author)

8)  J. Zhang, X.-F. Zhang, C. Zhou, Z.-Z. Wang, S.-J. Huang, X. Yao, Z.-L. Liang, T. Wu, J.-X. Li, Q. Yan, C.-L. Yang, H.-M. Jiang, H.-J. Huang, Y.-L. Xian, J. W.-K. Shih, M.-H. Ng, Y.-M. Li, J.-Z. Wang, F.-C. Zhu, N.-S. Xia. Protection against hepatitis E virus infection by naturally acquired and vaccine-induced immunity [J]. Clinical Microbiology and Infection, 2014, 20(6): O397-O405. (IF: 5.768)

9)  Ting Wu, Shou-Jie Huang, Feng-Cai Zhu, Xue-Feng Zhang, Xing Ai, Qiang Yan, Zhong-Ze Wang, Chang-Lin Yang, Han-Min Jiang, Xiao-Hui Liu, Meng Guo, Hai-Lian Du, Mun-Hon Ng, Jun Zhang, Ningshao Xia. Immunogenicity and safety of hepatitis E vaccine in healthy hepatitis B surface antigen positive adults [J]. Human Vaccines & Immunotherapeutics, 2013, 9(11): 2474-2479. (IF: 2.131)

10)  Ting Wu, Feng-Cai Zhu, Shou-Jie Huang, Xue-Feng Zhang, Zhong-Ze Wang, Jun Zhang, Ning-Shao Xia. Safety of hepatitis E vaccine for pregnant women: a preliminary analysis [J]. Hepatology, 2012, 55(6): 2038-2038. (IF: 12.003)

11)  Shoujie Huang, Xuefeng Zhang, Hanmin Jiang, Qiang Yan, Xing Ai, Yijun Wang, Jiaping Cai, Lang Jiang, Ting Wu, Zhongze Wang, Li Guan, J. Wai Kuo Shih, Mun-Hon Ng, Fengcai Zhu, Jun Zhang, Ningshao Xia. Profile of acute infectious markers in sporadic hepatitis E [J]. PloS one, 2010, 5(10): e13560. (IF: 4.411, Co-First Author)

12)  Feng-Cai Zhu, Jun Zhang, Xue-Feng Zhang, Cheng Zhou, Zhong-Ze Wang, Shou-Jie Huang, Hua Wang, Chang-Lin Yang, Han-Min Jiang, Jia-Ping Cai, Yi-Jun Wang, Xing Ai, Yue-Mei Hu, Quan Tang, Xin Yao, Qiang Yan, Yang-Ling Xian, Ting Wu, Yi-Min Li, Ji Miao, Mun-Hon Ng, James Wai-Kuo Shih, Ning-Shao Xia. Efficacy and safety of a recombinant hepatitis E vaccine in healthy adults: a large-scale, randomised, double-blind placebo-controlled, phase 3 trial [J]. The Lancet, 2010, 376(9744): 895-902. (IF: 33.633)

项 目

1)  主持一项国家自然科学基金项目(课题编号:81373061);参与1项863项目(课题编号:2006AA02A209),1项国家科技重大专项课题(课题编号:2012ZX09101316);

2)  做为主要研究成员完成国家一类新药重组戊型肝炎疫苗(大肠杆菌)Ⅲ期临床试验,该疫苗现已获得新药证书和生产文号,成为世界上第一个成功上市的戊肝疫苗;

3)  做为主要研究成员完成重组HPV16和18双价疫苗(大肠杆菌)Ⅰ、Ⅱ期临床试验;

4)  做为主要研究成员参与重组HPV16和18双价疫苗(大肠杆菌)Ⅲ期临床试验;

5)  做为主要研究成员参与重组(大肠杆菌)HPV6和11双价疫苗Ⅰ期临床试验。

获 奖

1)  2014年获得厦门大学校庆中国银行教科辅奖教金;

2)  2012年获得厦门大学公共卫生学院养生堂奖教金;

3)  2012年获得江苏省科学技术奖一等奖(排名:9);

4)  2011年获得戊肝疫苗新药证书和生产文号(国药证字S20110005)。

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